Selection and Identification of Skeletal-Muscle-Targeted RNA Aptamers
Selection and Identification of Skeletal-Muscle-Targeted RNA Aptamers
About this item
Full title
Author / Creator
Publisher
United States: Elsevier Inc
Journal title
Language
English
Formats
Publication information
Publisher
United States: Elsevier Inc
Subjects
More information
Scope and Contents
Contents
Oligonucleotide gene therapy has shown great promise for the treatment of muscular dystrophies. Nevertheless, the selective delivery to affected muscles has shown to be challenging because of their high representation in the body and the high complexity of their cell membranes. Current trials show loss of therapeutic molecules to non-target tissues...
Alternative Titles
Full title
Selection and Identification of Skeletal-Muscle-Targeted RNA Aptamers
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_6e90ec69d69243b4a73ae36a11dd9eab
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6e90ec69d69243b4a73ae36a11dd9eab
Other Identifiers
ISSN
2162-2531
E-ISSN
2162-2531
DOI
10.1016/j.omtn.2017.12.004
