The transcription factor ATF3 switches cell death from apoptosis to necroptosis in hepatic steatosis...
The transcription factor ATF3 switches cell death from apoptosis to necroptosis in hepatic steatosis in male mice
About this item
Full title
Author / Creator
Inaba, Yuka , Hashiuchi, Emi , Watanabe, Hitoshi , Kimura, Kumi , Oshima, Yu , Tsuchiya, Kohsuke , Murai, Shin , Takahashi, Chiaki , Matsumoto, Michihiro , Kitajima, Shigetaka , Yamamoto, Yasuhiko , Honda, Masao , Asahara, Shun-ichiro , Ravnskjaer, Kim , Horike, Shin-ichi , Kaneko, Shuichi , Kasuga, Masato , Nakano, Hiroyasu , Harada, Kenichi and Inoue, Hiroshi
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Hepatocellular death increases with hepatic steatosis aggravation, although its regulation remains unclear. Here we show that hepatic steatosis aggravation shifts the hepatocellular death mode from apoptosis to necroptosis, causing increased hepatocellular death. Our results reveal that the transcription factor ATF3 acts as a master regulator in th...
Alternative Titles
Full title
The transcription factor ATF3 switches cell death from apoptosis to necroptosis in hepatic steatosis in male mice
Authors, Artists and Contributors
Author / Creator
Hashiuchi, Emi
Watanabe, Hitoshi
Kimura, Kumi
Oshima, Yu
Tsuchiya, Kohsuke
Murai, Shin
Takahashi, Chiaki
Matsumoto, Michihiro
Kitajima, Shigetaka
Yamamoto, Yasuhiko
Honda, Masao
Asahara, Shun-ichiro
Ravnskjaer, Kim
Horike, Shin-ichi
Kaneko, Shuichi
Kasuga, Masato
Nakano, Hiroyasu
Harada, Kenichi
Inoue, Hiroshi
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_6e96d9a1b7674a218452a1194f8c9e95
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6e96d9a1b7674a218452a1194f8c9e95
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-35804-w
