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1399 Identification of alternative splicing-derived targets for TCR-T cell therapies

1399 Identification of alternative splicing-derived targets for TCR-T cell therapies

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6eb8da73e5144043a5ee8c9d694121ba

1399 Identification of alternative splicing-derived targets for TCR-T cell therapies

About this item

Full title

1399 Identification of alternative splicing-derived targets for TCR-T cell therapies

Publisher

London: BMJ Publishing Group Ltd

Journal title

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1554-A1556

Language

English

Formats

Publication information

Publisher

London: BMJ Publishing Group Ltd

More information

Scope and Contents

Contents

BackgroundT cells genetically modified to express a high affinity T cell receptor (TCR) have considerable potential for the treatment of cancer, however identifying immunogenic, tumor-specific targets remains a challenge. Recent transcriptomic analysis has shown that splicing mutations are frequently found across many different cancer types and can...

Alternative Titles

Full title

1399 Identification of alternative splicing-derived targets for TCR-T cell therapies

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6eb8da73e5144043a5ee8c9d694121ba

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6eb8da73e5144043a5ee8c9d694121ba

Other Identifiers

E-ISSN

2051-1426

DOI

10.1136/jitc-2023-SITC2023.1399

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