1399 Identification of alternative splicing-derived targets for TCR-T cell therapies
1399 Identification of alternative splicing-derived targets for TCR-T cell therapies
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London: BMJ Publishing Group Ltd
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English
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London: BMJ Publishing Group Ltd
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BackgroundT cells genetically modified to express a high affinity T cell receptor (TCR) have considerable potential for the treatment of cancer, however identifying immunogenic, tumor-specific targets remains a challenge. Recent transcriptomic analysis has shown that splicing mutations are frequently found across many different cancer types and can...
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1399 Identification of alternative splicing-derived targets for TCR-T cell therapies
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TN_cdi_doaj_primary_oai_doaj_org_article_6eb8da73e5144043a5ee8c9d694121ba
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6eb8da73e5144043a5ee8c9d694121ba
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E-ISSN
2051-1426
DOI
10.1136/jitc-2023-SITC2023.1399