Enhanced CD4+ and CD8+ T cell infiltrate within convex hull defined pancreatic islet borders as auto...
Enhanced CD4+ and CD8+ T cell infiltrate within convex hull defined pancreatic islet borders as autoimmune diabetes progresses
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The notion that T cell insulitis increases as type 1 diabetes (T1D) develops is unsurprising, however, the quantitative analysis of CD4
+
and CD8
+
T cells within the islet mass is complex and limited with standard approaches. Optical microscopy is an important and widely used method to evaluate immune cell infiltration into pancreatic...
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Full title
Enhanced CD4+ and CD8+ T cell infiltrate within convex hull defined pancreatic islet borders as autoimmune diabetes progresses
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TN_cdi_doaj_primary_oai_doaj_org_article_6ed0acc70c384d58b92cd026ebe5a4ee
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6ed0acc70c384d58b92cd026ebe5a4ee
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-96327-2
