S-Adenosylmethionine Treatment of Colorectal Cancer Cell Lines Alters DNA Methylation, DNA Repair an...
S-Adenosylmethionine Treatment of Colorectal Cancer Cell Lines Alters DNA Methylation, DNA Repair and Tumor Progression-Related Gene Expression
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Zsigrai, Sára , Kalmár, Alexandra , Nagy, Zsófia B , Barták, Barbara K , Valcz, Gábor , Szigeti, Krisztina A , Galamb, Orsolya , Dankó, Titanilla , Sebestyén, Anna , Barna, Gábor , Szabó, Vanessza , Pipek, Orsolya , Medgyes-Horváth, Anna , Csabai, István , Tulassay, Zsolt , Igaz, Péter , Takács, István and Molnár, Béla
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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Global DNA hypomethylation is a characteristic feature of colorectal carcinoma (CRC). The tumor inhibitory effect of S-adenosylmethionine (SAM) methyl donor has been described in certain cancers including CRC. However, the molecular impact of SAM treatment on CRC cell lines with distinct genetic features has not been evaluated comprehensively. HT-2...
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S-Adenosylmethionine Treatment of Colorectal Cancer Cell Lines Alters DNA Methylation, DNA Repair and Tumor Progression-Related Gene Expression
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TN_cdi_doaj_primary_oai_doaj_org_article_6ed380cf3d6b4ef4974e97eea8289f16
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6ed380cf3d6b4ef4974e97eea8289f16
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ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells9081864