The BET inhibitor apabetalone decreases neuroendothelial proinflammatory activation in vitro and in...
The BET inhibitor apabetalone decreases neuroendothelial proinflammatory activation in vitro and in a mouse model of systemic inflammation
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Publisher
Germany: De Gruyter
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Language
English
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Publisher
Germany: De Gruyter
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Contents
Brain vascular inflammation is characterized by endothelial activation and immune cell recruitment to the blood vessel wall, potentially causing a breach in the blood – brain barrier, brain parenchyma inflammation, and a decline of cognitive function. The clinical-stage small molecule, apabetalone, reduces circulating vascular endothelial inflammat...
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Full title
The BET inhibitor apabetalone decreases neuroendothelial proinflammatory activation in vitro and in a mouse model of systemic inflammation
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TN_cdi_doaj_primary_oai_doaj_org_article_6ed3c2d040cb42c6909638ca4b5fbb62
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6ed3c2d040cb42c6909638ca4b5fbb62
Other Identifiers
ISSN
2081-3856,2081-6936
E-ISSN
2081-6936
DOI
10.1515/tnsci-2022-0332
