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Lasp1 regulates adherens junction dynamics and fibroblast transformation in destructive arthritis

Lasp1 regulates adherens junction dynamics and fibroblast transformation in destructive arthritis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6eeabbe32b3249c9843c922ebc496340

Lasp1 regulates adherens junction dynamics and fibroblast transformation in destructive arthritis

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The LIM and SH3 domain protein 1 (Lasp1) was originally cloned from metastatic breast cancer and characterised as an adaptor molecule associated with tumourigenesis and cancer cell invasion. However, the regulation of Lasp1 and its function in the aggressive transformation of cells is unclear. Here we use integrative epigenomic profiling of invasiv...

Alternative Titles

Full title

Lasp1 regulates adherens junction dynamics and fibroblast transformation in destructive arthritis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6eeabbe32b3249c9843c922ebc496340

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6eeabbe32b3249c9843c922ebc496340

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-23706-8

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