Stromal FOXF2 suppresses prostate cancer progression and metastasis by enhancing antitumor immunity
Stromal FOXF2 suppresses prostate cancer progression and metastasis by enhancing antitumor immunity
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Cancer-associated fibroblasts (CAFs) mediate an immunosuppressive effect, but the underlying mechanism remains incompletely defined. Here we show that increasing prostatic stromal
Foxf2
suppresses the growth and progression of both syngeneic and autochthonous mouse prostate cancer models in an immunocompetent context. Mechanistically, Foxf2 m...
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Full title
Stromal FOXF2 suppresses prostate cancer progression and metastasis by enhancing antitumor immunity
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TN_cdi_doaj_primary_oai_doaj_org_article_6ef1b8477dc94cb884e5bb6309eb3423
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6ef1b8477dc94cb884e5bb6309eb3423
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-34665-z
