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Impact of common ALDH2 inactivating mutation and alcohol consumption on Alzheimer’s disease

Impact of common ALDH2 inactivating mutation and alcohol consumption on Alzheimer’s disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6ef756752fcf4dc983738f2a40b4b757

Impact of common ALDH2 inactivating mutation and alcohol consumption on Alzheimer’s disease

About this item

Full title

Impact of common ALDH2 inactivating mutation and alcohol consumption on Alzheimer’s disease

Publisher

Lausanne: Frontiers Research Foundation

Journal title

Frontiers in aging neuroscience, 2023-08, Vol.15, p.1223977

Language

English

Formats

Publication information

Publisher

Lausanne: Frontiers Research Foundation

More information

Scope and Contents

Contents

Aldehyde dehydrogenase 2 (ALDH2) is an enzyme found in the mitochondrial matrix that plays a central role in alcohol and aldehyde metabolism. A common ALDH2 polymorphism in East Asians descent (called ALDH2*2 or E504K missense variant, SNP ID: rs671), present in approximately 8% of the world’s population, has been associated with a variety of disea...

Alternative Titles

Full title

Impact of common ALDH2 inactivating mutation and alcohol consumption on Alzheimer’s disease

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6ef756752fcf4dc983738f2a40b4b757

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6ef756752fcf4dc983738f2a40b4b757

Other Identifiers

ISSN

1663-4365

E-ISSN

1663-4365

DOI

10.3389/fnagi.2023.1223977

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