Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results i...
Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The ongoing Corona Virus Disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has emphasized the urgent need for antiviral therapeutics. The viral RNA-dependent-RNA-polymerase (RdRp) is a promising target with polymerase inhibitors successfully used for the treatment of several viral diseases. We...
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Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis
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TN_cdi_doaj_primary_oai_doaj_org_article_6f077279cc5545ac8b6524fe1944a7d7
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6f077279cc5545ac8b6524fe1944a7d7
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-18463-z
