Macrophage specific restoration of the Nrf2 gene in whole-body knockout mice ameliorates steatohepat...
Macrophage specific restoration of the Nrf2 gene in whole-body knockout mice ameliorates steatohepatitis induced by lipopolysaccharide from Porphyromonas gingivalis through enhanced hepatic clearance
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San Francisco, CA USA: Public Library of Science
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Language
English
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Publisher
San Francisco, CA USA: Public Library of Science
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Contents
Lipopolysaccharide (LPS) derived from
Porphyromonas gingivalis
(
P
.
g
.), which causes periodontal disease, contributes to the development of non-alcoholic steatohepatitis (NASH). We investigated the role of Nrf2, an antioxidative stress sensor, in macrophages in the development of NASH induced by LPS from
P
.
g
. We...
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Full title
Macrophage specific restoration of the Nrf2 gene in whole-body knockout mice ameliorates steatohepatitis induced by lipopolysaccharide from Porphyromonas gingivalis through enhanced hepatic clearance
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TN_cdi_doaj_primary_oai_doaj_org_article_6f0bed8f5a404bd8a3d329b51b60fb10
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6f0bed8f5a404bd8a3d329b51b60fb10
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0291880
