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Dual therapeutic targeting of MYC and JUNB transcriptional programs for enhanced anti-myeloma activi...

Dual therapeutic targeting of MYC and JUNB transcriptional programs for enhanced anti-myeloma activi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6f0fada8d8aa46c2a07a49b9d5a5c9ab

Dual therapeutic targeting of MYC and JUNB transcriptional programs for enhanced anti-myeloma activity

About this item

Full title

Dual therapeutic targeting of MYC and JUNB transcriptional programs for enhanced anti-myeloma activity

Publisher

London: Nature Publishing Group UK

Journal title

Blood cancer journal (New York), 2024-08, Vol.14 (1), p.138-12, Article 138

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Deregulation of transcription factors (TFs) leading to uncontrolled proliferation of tumor cells within the microenvironment represents a hallmark of cancer. However, the biological and clinical impact of transcriptional interference, particularly in multiple myeloma (MM) cells, remains poorly understood. The present study shows for the first time...

Alternative Titles

Full title

Dual therapeutic targeting of MYC and JUNB transcriptional programs for enhanced anti-myeloma activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6f0fada8d8aa46c2a07a49b9d5a5c9ab

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6f0fada8d8aa46c2a07a49b9d5a5c9ab

Other Identifiers

ISSN

2044-5385

E-ISSN

2044-5385

DOI

10.1038/s41408-024-01117-4

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