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Cholesterol-dependent amyloid β production: space for multifarious interactions between amyloid prec...

Cholesterol-dependent amyloid β production: space for multifarious interactions between amyloid prec...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6f3c8bd9b9994db2951afd8edf5c355a

Cholesterol-dependent amyloid β production: space for multifarious interactions between amyloid precursor protein, secretases, and cholesterol

About this item

Full title

Cholesterol-dependent amyloid β production: space for multifarious interactions between amyloid precursor protein, secretases, and cholesterol

Publisher

London: BioMed Central

Journal title

Cell & bioscience, 2023-09, Vol.13 (1), p.1-23, Article 171

Language

English

Formats

Publication information

Publisher

London: BioMed Central

More information

Scope and Contents

Contents

Amyloid β is considered a key player in the development and progression of Alzheimer’s disease (AD). Many studies investigating the effect of statins on lowering cholesterol suggest that there may be a link between cholesterol levels and AD pathology. Since cholesterol is one of the most abundant lipid molecules, especially in brain tissue, it affe...

Alternative Titles

Full title

Cholesterol-dependent amyloid β production: space for multifarious interactions between amyloid precursor protein, secretases, and cholesterol

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6f3c8bd9b9994db2951afd8edf5c355a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6f3c8bd9b9994db2951afd8edf5c355a

Other Identifiers

ISSN

2045-3701

E-ISSN

2045-3701

DOI

10.1186/s13578-023-01127-y

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