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Exploring the associations between transcript levels and fluxes in constraint-based models of metabo...

Exploring the associations between transcript levels and fluxes in constraint-based models of metabo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6f4431891a6e4a50b5861b087c64c3c3

Exploring the associations between transcript levels and fluxes in constraint-based models of metabolism

About this item

Full title

Exploring the associations between transcript levels and fluxes in constraint-based models of metabolism

Publisher

London: BioMed Central Ltd

Journal title

BMC bioinformatics, 2021-11, Vol.22 (1), p.1-574, Article 574

Language

English

Formats

Publication information

Publisher

London: BioMed Central Ltd

More information

Scope and Contents

Contents

Several computational methods have been developed that integrate transcriptomics data with genome-scale metabolic reconstructions to increase accuracy of inferences of intracellular metabolic flux distributions. Even though existing methods use transcript abundances as a proxy for enzyme activity, each method uses a different hypothesis and assumpt...

Alternative Titles

Full title

Exploring the associations between transcript levels and fluxes in constraint-based models of metabolism

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6f4431891a6e4a50b5861b087c64c3c3

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6f4431891a6e4a50b5861b087c64c3c3

Other Identifiers

ISSN

1471-2105

E-ISSN

1471-2105

DOI

10.1186/s12859-021-04488-8

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