Targeting fidelity of adenine and cytosine base editors in mouse embryos
Targeting fidelity of adenine and cytosine base editors in mouse embryos
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Base editing directly converts a target base pair into a different base pair in the genome of living cells without introducing double-stranded DNA breaks. While cytosine base editors (CBE) and adenine base editors (ABE) are used to install and correct point mutations in a wide range of organisms, the extent and distribution of off-target edits in m...
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Full title
Targeting fidelity of adenine and cytosine base editors in mouse embryos
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TN_cdi_doaj_primary_oai_doaj_org_article_6f5a2eab54b647bf9d594d5cbd192da5
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6f5a2eab54b647bf9d594d5cbd192da5
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-07322-7
