DENR promotes translation reinitiation via ribosome recycling to drive expression of oncogenes inclu...
DENR promotes translation reinitiation via ribosome recycling to drive expression of oncogenes including ATF4
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Translation efficiency varies considerably between different mRNAs, thereby impacting protein expression. Translation of the stress response master-regulator ATF4 increases upon stress, but the molecular mechanisms are not well understood. We discover here that translation factors DENR, MCTS1 and eIF2D are required to induce ATF4 translation upon s...
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DENR promotes translation reinitiation via ribosome recycling to drive expression of oncogenes including ATF4
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TN_cdi_doaj_primary_oai_doaj_org_article_6f5c73c82bd545db83b3c936664b634c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6f5c73c82bd545db83b3c936664b634c
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-18452-2
