NPT100-18A rescues mitochondrial oxidative stress and neuronal degeneration in human iPSC-based Park...
NPT100-18A rescues mitochondrial oxidative stress and neuronal degeneration in human iPSC-based Parkinson’s model
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Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Contents
Parkinson's disease (PD) is a neurodegenerative disorder characterized by protein aggregates mostly consisting of misfolded alpha-synuclein (αSyn). Progressive degeneration of midbrain dopaminergic neurons (mDANs) and nigrostriatal projections results in severe motor symptoms. While the preferential loss of mDANs has not been fully understood yet,...
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NPT100-18A rescues mitochondrial oxidative stress and neuronal degeneration in human iPSC-based Parkinson’s model
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TN_cdi_doaj_primary_oai_doaj_org_article_6f92aa5c48fa41f7b60e8465525546ae
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6f92aa5c48fa41f7b60e8465525546ae
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ISSN
1471-2202
E-ISSN
1471-2202
DOI
10.1186/s12868-025-00926-y
