P63 and P73 Activation in Cancers with p53 Mutation
P63 and P73 Activation in Cancers with p53 Mutation
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Publisher
Basel: MDPI AG
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Language
English
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Publisher
Basel: MDPI AG
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Contents
The members of the p53 family comprise p53, p63, and p73, and full-length isoforms of the p53 family have a tumor suppressor function. However, p53, but not p63 or p73, has a high mutation rate in cancers causing it to lose its tumor suppressor function. The top and second-most prevalent p53 mutations are missense and nonsense mutations, respective...
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Full title
P63 and P73 Activation in Cancers with p53 Mutation
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TN_cdi_doaj_primary_oai_doaj_org_article_6fbba4656e7444acaf561a3bb67fda31
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6fbba4656e7444acaf561a3bb67fda31
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ISSN
2227-9059
E-ISSN
2227-9059
DOI
10.3390/biomedicines10071490
