The Molecular Basis of the Intrinsic and Acquired Resistance to Azole Antifungals in Aspergillus fum...
The Molecular Basis of the Intrinsic and Acquired Resistance to Azole Antifungals in Aspergillus fumigatus
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Publisher
Switzerland: MDPI AG
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Language
English
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Switzerland: MDPI AG
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Contents
is intrinsically resistant to the widely used antifungal fluconazole, and therapeutic failure can result from acquired resistance to voriconazole, the primary treatment for invasive aspergillosis. The molecular basis of substrate specificity and innate and acquired resistance of
to azole drugs were addressed using crystal structures, molecular m...
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Full title
The Molecular Basis of the Intrinsic and Acquired Resistance to Azole Antifungals in Aspergillus fumigatus
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TN_cdi_doaj_primary_oai_doaj_org_article_7001f2668c7143aab0fb22f542db1f27
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7001f2668c7143aab0fb22f542db1f27
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ISSN
2309-608X
E-ISSN
2309-608X
DOI
10.3390/jof10120820