Muscarinic receptor agonists and positive allosteric modulators in animal models of psychosis: proto...
Muscarinic receptor agonists and positive allosteric modulators in animal models of psychosis: protocol for a systematic review and meta-analysis [version 2; peer review: 2 approved with reservations]
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Author / Creator
Siafis, Spyridon , Nomura, Nobuyuki , Schneider-Thoma, Johannes , Bighelli, Irene , Bannach-Brown, Alexandra , Ramage, Fiona J. , Tinsdeall, Francesca , Mantas, Ioannis , Jauhar, Sameer , Natesan, Sridhar , Vernon, Anthony C. , de Bartolomeis, Andrea , Hölter, Sabine M. , Drude, Natascha I. , Tölch, Ulf , Hansen, Wulf-Peter , Chiocchia, Virginia , Howes, Oliver D. , Priller, Josef , Macleod, Malcolm R. , Salanti, Georgia and Leucht, Stefan
Publisher
England: F1000 Research Limited
Journal title
Language
English
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Publication information
Publisher
England: F1000 Research Limited
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Scope and Contents
Contents
Background Muscarinic receptor agonism and positive allosteric modulation is a promising mechanism of action for treating psychosis, not present in most D2R-blocking antipsychotics. Xanomeline, an M1/M4-preferring agonist, has shown efficacy in late-stage clinical trials, with more compounds being investigated. Therefore, we aim to synthesize evide...
Alternative Titles
Full title
Muscarinic receptor agonists and positive allosteric modulators in animal models of psychosis: protocol for a systematic review and meta-analysis [version 2; peer review: 2 approved with reservations]
Authors, Artists and Contributors
Author / Creator
Nomura, Nobuyuki
Schneider-Thoma, Johannes
Bighelli, Irene
Bannach-Brown, Alexandra
Ramage, Fiona J.
Tinsdeall, Francesca
Mantas, Ioannis
Jauhar, Sameer
Natesan, Sridhar
Vernon, Anthony C.
de Bartolomeis, Andrea
Hölter, Sabine M.
Drude, Natascha I.
Tölch, Ulf
Hansen, Wulf-Peter
Chiocchia, Virginia
Howes, Oliver D.
Priller, Josef
Macleod, Malcolm R.
Salanti, Georgia
Leucht, Stefan
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_701c1c0279bb45f2861c199cba7cbd42
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_701c1c0279bb45f2861c199cba7cbd42
Other Identifiers
ISSN
2046-1402
E-ISSN
2046-1402
DOI
10.12688/f1000research.155356.2
