ASFV pS183L protein negatively regulates RLR-mediated antiviral signalling by blocking MDA5 oligomer...
ASFV pS183L protein negatively regulates RLR-mediated antiviral signalling by blocking MDA5 oligomerisation
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
The retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs) are major sensors against viral infection, but their roles in DNA virus infection largely remain unknown. This study found that a previously uncharacterised protein, pS183L, negatively regulates RLR signalling by suppressing MDA5 oligomerisation. Specifically, we showed that the overe...
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Full title
ASFV pS183L protein negatively regulates RLR-mediated antiviral signalling by blocking MDA5 oligomerisation
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TN_cdi_doaj_primary_oai_doaj_org_article_7058438c1f564899ac43d2cd895af813
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7058438c1f564899ac43d2cd895af813
Other Identifiers
ISSN
1297-9716,0928-4249
E-ISSN
1297-9716
DOI
10.1186/s13567-025-01488-x
