Direct and indirect salt effects on homotypic phase separation
Direct and indirect salt effects on homotypic phase separation
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England: eLife Sciences Publications Ltd
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English
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England: eLife Sciences Publications Ltd
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The low-complexity domain of hnRNPA1 (A1-LCD) phase separates in a salt-dependent manner. Unlike many intrinsically disordered proteins (IDPs) whose phase separation is suppressed by increasing salt concentrations, the phase separation of A1-LCD is promoted by >100 mM NaCl. To investigate the atypical salt effect on A1-LCD phase separation, we carr...
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Direct and indirect salt effects on homotypic phase separation
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TN_cdi_doaj_primary_oai_doaj_org_article_7081e86f55ef4d79be5f49096a44498a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7081e86f55ef4d79be5f49096a44498a
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.100282
