Plasma neurofilament light chain is associated with cognitive decline in non-dementia older adults
Plasma neurofilament light chain is associated with cognitive decline in non-dementia older adults
About this item
Full title
Author / Creator
He, Lingxiao , Morley, John E. , Aggarwal, Geetika , Nguyen, Andrew D. , Vellas, Bruno , de Souto Barreto, Philipe , Co-Investigators in associated centres , Psychologists , PET scans group , MAPT Study Group , MRI group , Multidomain group , Project leader , Medico-economics group , DSA Group , Biological sample collection , the MAPT/DSA Group , CRA , Investigators , Safety management , Coordination , Principal investigator , Methodology, statistical analysis and data management and MAPT/DSA Group
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Neurofilament light chain (NfL) has been associated with cognitive status in multiple neurodegenerative conditions. Studies about plasma NfL and cognitive decline in older adults are still limited. 504 older adults (median age 75 years) who expressed memory complaints were selected from the Multidomain Alzheimer’s Preventive Trial (MAPT) and were c...
Alternative Titles
Full title
Plasma neurofilament light chain is associated with cognitive decline in non-dementia older adults
Authors, Artists and Contributors
Author / Creator
Morley, John E.
Aggarwal, Geetika
Nguyen, Andrew D.
Vellas, Bruno
de Souto Barreto, Philipe
Co-Investigators in associated centres
Psychologists
PET scans group
MAPT Study Group
MRI group
Multidomain group
Project leader
Medico-economics group
DSA Group
Biological sample collection
the MAPT/DSA Group
CRA
Investigators
Safety management
Coordination
Principal investigator
Methodology, statistical analysis and data management
MAPT/DSA Group
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_7088dec790fc4066a1ece005c7ffac11
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7088dec790fc4066a1ece005c7ffac11
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-91038-0
