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Effects of Tocilizumab on Inflammation and Iron Metabolism in Critically Ill Patients with COVID-19

Effects of Tocilizumab on Inflammation and Iron Metabolism in Critically Ill Patients with COVID-19

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_70b918936a44446098dee3c1e6d55395

Effects of Tocilizumab on Inflammation and Iron Metabolism in Critically Ill Patients with COVID-19

About this item

Full title

Effects of Tocilizumab on Inflammation and Iron Metabolism in Critically Ill Patients with COVID-19

Publisher

Switzerland: MDPI AG

Journal title

Pharmaceutics, 2023-02, Vol.15 (2), p.646

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

COVID-19 produces cytokine-mediated persistent inflammation and is associated with elevated iron stores and low circulating iron. It is believed that central to the pathophysiological mechanism is interleukin 6 and hepcidin. A state of iron overload, termed hyperferritinemia, and inflammatory anemia take place. Both conditions are linked to a worse...

Alternative Titles

Full title

Effects of Tocilizumab on Inflammation and Iron Metabolism in Critically Ill Patients with COVID-19

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_70b918936a44446098dee3c1e6d55395

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_70b918936a44446098dee3c1e6d55395

Other Identifiers

ISSN

1999-4923

E-ISSN

1999-4923

DOI

10.3390/pharmaceutics15020646

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