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Biologic Complexity in Sickle Cell Disease: Implications for Developing Targeted Therapeutics

Biologic Complexity in Sickle Cell Disease: Implications for Developing Targeted Therapeutics

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_70e640b1b5ad41d683e8c8a6de04f230

Biologic Complexity in Sickle Cell Disease: Implications for Developing Targeted Therapeutics

About this item

Full title

Biologic Complexity in Sickle Cell Disease: Implications for Developing Targeted Therapeutics

Author / Creator

Publisher

Cairo, Egypt: Hindawi Publishing Corporation

Journal title

TheScientificWorld, 2013-01, Vol.2013 (2013), p.1-12

Language

English

Formats

Publication information

Publisher

Cairo, Egypt: Hindawi Publishing Corporation

More information

Scope and Contents

Contents

Current therapy for sickle cell disease (SCD) is limited to supportive treatment of complications, red blood cell transfusions, hydroxyurea, and stem cell transplantation. Difficulty in the translation of mechanistically based therapies may be the result of a reductionist approach focused on individual pathways, without having demonstrated their re...

Alternative Titles

Full title

Biologic Complexity in Sickle Cell Disease: Implications for Developing Targeted Therapeutics

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_70e640b1b5ad41d683e8c8a6de04f230

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_70e640b1b5ad41d683e8c8a6de04f230

Other Identifiers

ISSN

2356-6140

E-ISSN

1537-744X

DOI

10.1155/2013/694146

How to access this item