Biologic Complexity in Sickle Cell Disease: Implications for Developing Targeted Therapeutics
Biologic Complexity in Sickle Cell Disease: Implications for Developing Targeted Therapeutics
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Publisher
Cairo, Egypt: Hindawi Publishing Corporation
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Language
English
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Publisher
Cairo, Egypt: Hindawi Publishing Corporation
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Contents
Current therapy for sickle cell disease (SCD) is limited to supportive treatment of complications, red blood cell transfusions, hydroxyurea, and stem cell transplantation. Difficulty in the translation of mechanistically based therapies may be the result of a reductionist approach focused on individual pathways, without having demonstrated their re...
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Biologic Complexity in Sickle Cell Disease: Implications for Developing Targeted Therapeutics
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TN_cdi_doaj_primary_oai_doaj_org_article_70e640b1b5ad41d683e8c8a6de04f230
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_70e640b1b5ad41d683e8c8a6de04f230
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ISSN
2356-6140
E-ISSN
1537-744X
DOI
10.1155/2013/694146