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Serine/threonine kinase 11 (STK11) associated adnexal tumors: from biology to therapeutic impact

Serine/threonine kinase 11 (STK11) associated adnexal tumors: from biology to therapeutic impact

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7154d3d77baa4207b090dc6ed24bb985

Serine/threonine kinase 11 (STK11) associated adnexal tumors: from biology to therapeutic impact

About this item

Full title

Serine/threonine kinase 11 (STK11) associated adnexal tumors: from biology to therapeutic impact

Publisher

England: BioMed Central Ltd

Journal title

Human Genomics, 2025-03, Vol.19 (1), p.28-13, Article 28

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Female adnexal malignancies, while relatively uncommon, exhibit high mortality rates due to often-late diagnosis. The serine/threonine kinase 11 (STK11) is a tumor suppressor gene, and its inactivation or mutation often leads to an autosomal dominant genetic disorder known as Peutz-Jeghers syndrome (PJS), which is associated with ovarian and cervic...

Alternative Titles

Full title

Serine/threonine kinase 11 (STK11) associated adnexal tumors: from biology to therapeutic impact

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_7154d3d77baa4207b090dc6ed24bb985

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7154d3d77baa4207b090dc6ed24bb985

Other Identifiers

ISSN

1479-7364,1473-9542

E-ISSN

1479-7364

DOI

10.1186/s40246-025-00741-w

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