The amide derivative of anticopalic acid induces non-apoptotic cell death in triple-negative breast...
The amide derivative of anticopalic acid induces non-apoptotic cell death in triple-negative breast cancer cells by inhibiting FAK activation
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Anticopalic acid (
ACP
), a labdane type diterpenoid obtained from
Kaempferia elegans
rhizomes, together with 21 semi-synthetic derivatives, were evaluated for their cancer cytotoxic activity. Most derivatives displayed higher cytotoxic activity than the parent compound
ACP
in a panel of nine cancer cell lines. Among the tested co...
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Full title
The amide derivative of anticopalic acid induces non-apoptotic cell death in triple-negative breast cancer cells by inhibiting FAK activation
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TN_cdi_doaj_primary_oai_doaj_org_article_716dd1af9a5b4261b7eff9fcdbe2344d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_716dd1af9a5b4261b7eff9fcdbe2344d
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-40669-6
