Lipopolysaccharide distinctively alters human microglia transcriptomes to resemble microglia from Al...
Lipopolysaccharide distinctively alters human microglia transcriptomes to resemble microglia from Alzheimer's disease mouse models
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Publisher
England: The Company of Biologists
Journal title
Language
English
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Publisher
England: The Company of Biologists
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Contents
Alzheimer's disease (AD) is the most common form of dementia, and risk-influencing genetics implicates microglia and neuroimmunity in the pathogenesis of AD. Induced pluripotent stem cell (iPSC)-derived microglia (iPSC-microglia) are increasingly used as a model of AD, but the relevance of historical immune stimuli to model AD is unclear. We perfor...
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Full title
Lipopolysaccharide distinctively alters human microglia transcriptomes to resemble microglia from Alzheimer's disease mouse models
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TN_cdi_doaj_primary_oai_doaj_org_article_71d2d166952149deaacfd3fb1e483bae
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_71d2d166952149deaacfd3fb1e483bae
Other Identifiers
ISSN
1754-8403
E-ISSN
1754-8411
DOI
10.1242/dmm.049349
