Fat mass and obesity-associated protein regulates RNA methylation associated with depression-like be...
Fat mass and obesity-associated protein regulates RNA methylation associated with depression-like behavior in mice
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Liu, Shu , Xiu, Jianbo , Zhu, Caiyun , Meng, Kexin , Li, Chen , Han, Rongrong , Du, Tingfu , Li, Lanlan , Xu, Lingdan , Liu, Renjie , Zhu, Wanwan , Shen, Yan and Xu, Qi
Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Post-transcriptional modifications of RNA, such as RNA methylation, can epigenetically regulate behavior, for instance learning and memory. However, it is unclear whether RNA methylation plays a critical role in the pathophysiology of major depression disorder (MDD). Here, we report that expression of the fat mass and obesity associated gene (FTO),...
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Fat mass and obesity-associated protein regulates RNA methylation associated with depression-like behavior in mice
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TN_cdi_doaj_primary_oai_doaj_org_article_71f4d2ea3f6b44e1a1921e645f08bb41
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_71f4d2ea3f6b44e1a1921e645f08bb41
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-27044-7