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Fat mass and obesity-associated protein regulates RNA methylation associated with depression-like be...

Fat mass and obesity-associated protein regulates RNA methylation associated with depression-like be...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_71f4d2ea3f6b44e1a1921e645f08bb41

Fat mass and obesity-associated protein regulates RNA methylation associated with depression-like behavior in mice

About this item

Full title

Fat mass and obesity-associated protein regulates RNA methylation associated with depression-like behavior in mice

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2021-11, Vol.12 (1), p.6937-13, Article 6937

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Post-transcriptional modifications of RNA, such as RNA methylation, can epigenetically regulate behavior, for instance learning and memory. However, it is unclear whether RNA methylation plays a critical role in the pathophysiology of major depression disorder (MDD). Here, we report that expression of the fat mass and obesity associated gene (FTO),...

Alternative Titles

Full title

Fat mass and obesity-associated protein regulates RNA methylation associated with depression-like behavior in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_71f4d2ea3f6b44e1a1921e645f08bb41

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_71f4d2ea3f6b44e1a1921e645f08bb41

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-27044-7

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