Uncovering the signaling landscape controlling breast cancer cell migration identifies novel metasta...
Uncovering the signaling landscape controlling breast cancer cell migration identifies novel metastasis driver genes
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Author / Creator
Koedoot, Esmee , Fokkelman, Michiel , Rogkoti, Vasiliki-Maria , Smid, Marcel , van de Sandt, Iris , de Bont, Hans , Pont, Chantal , Klip, Janna E. , Wink, Steven , Timmermans, Mieke A. , Wiemer, Erik A. C. , Stoilov, Peter , Foekens, John A. , Le Dévédec, Sylvia E. , Martens, John W. M. and van de Water, Bob
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Ttriple-negative breast cancer (TNBC) is an aggressive and highly metastatic breast cancer subtype. Enhanced TNBC cell motility is a prerequisite of TNBC cell dissemination. Here, we apply an imaging-based RNAi phenotypic cell migration screen using two highly motile TNBC cell lines (Hs578T and MDA-MB-231) to provide a repository of signaling deter...
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Full title
Uncovering the signaling landscape controlling breast cancer cell migration identifies novel metastasis driver genes
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_720606fcf5f54cc0ae38a7db6f491bec
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_720606fcf5f54cc0ae38a7db6f491bec
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-11020-3