TOM20-mediated transfer of Bcl2 from ER to MAM and mitochondria upon induction of apoptosis
TOM20-mediated transfer of Bcl2 from ER to MAM and mitochondria upon induction of apoptosis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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In this work, we have explored the subcellular localization of Bcl2, a major antiapoptotic protein. In U251 glioma cells, we found that Bcl2 is localized mainly in the ER and is translocated to MAM and mitochondria upon induction of apoptosis; this mitochondrial transfer was not restricted to the demonstrator cell line, even if cell-specific modula...
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TOM20-mediated transfer of Bcl2 from ER to MAM and mitochondria upon induction of apoptosis
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TN_cdi_doaj_primary_oai_doaj_org_article_72336e4f9ad24e9291ef2c91af411e5c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_72336e4f9ad24e9291ef2c91af411e5c
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2041-4889
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2041-4889
DOI
10.1038/s41419-021-03471-8