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TOM20-mediated transfer of Bcl2 from ER to MAM and mitochondria upon induction of apoptosis

TOM20-mediated transfer of Bcl2 from ER to MAM and mitochondria upon induction of apoptosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_72336e4f9ad24e9291ef2c91af411e5c

TOM20-mediated transfer of Bcl2 from ER to MAM and mitochondria upon induction of apoptosis

About this item

Full title

TOM20-mediated transfer of Bcl2 from ER to MAM and mitochondria upon induction of apoptosis

Publisher

London: Nature Publishing Group UK

Journal title

Cell death & disease, 2021-02, Vol.12 (2), p.182-182, Article 182

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

In this work, we have explored the subcellular localization of Bcl2, a major antiapoptotic protein. In U251 glioma cells, we found that Bcl2 is localized mainly in the ER and is translocated to MAM and mitochondria upon induction of apoptosis; this mitochondrial transfer was not restricted to the demonstrator cell line, even if cell-specific modula...

Alternative Titles

Full title

TOM20-mediated transfer of Bcl2 from ER to MAM and mitochondria upon induction of apoptosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_72336e4f9ad24e9291ef2c91af411e5c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_72336e4f9ad24e9291ef2c91af411e5c

Other Identifiers

ISSN

2041-4889

E-ISSN

2041-4889

DOI

10.1038/s41419-021-03471-8

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