Alpha Lipoic Acid Modulated High Glucose-Induced Rat Mesangial Cell Dysfunction via mTOR/p70S6K/4E-B...
Alpha Lipoic Acid Modulated High Glucose-Induced Rat Mesangial Cell Dysfunction via mTOR/p70S6K/4E-BP1 Pathway
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Author / Creator
Wang, Guan , Shao, Ying , Zhou, Yue-hong , Wu, Can , Lv, Chuan and Wang, Qiu-yue
Publisher
Cairo, Egypt: Hindawi Limiteds
Journal title
Language
English
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Publication information
Publisher
Cairo, Egypt: Hindawi Limiteds
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Scope and Contents
Contents
The aim of this study was to investigate whether alpha lipoic acid (LA) regulates high glucose-induced mesangial cell proliferation and extracellular matrix production via mTOR/p70S6K/4E-BP1 signaling. The effect of LA on high glucose-induced cell proliferation, fibronectin (FN), and collagen type I (collagen-I) expression and its mechanisms were e...
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Full title
Alpha Lipoic Acid Modulated High Glucose-Induced Rat Mesangial Cell Dysfunction via mTOR/p70S6K/4E-BP1 Pathway
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_724a960349654e7c8e9dfc1f08bf75de
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_724a960349654e7c8e9dfc1f08bf75de
Other Identifiers
ISSN
1687-8337
E-ISSN
1687-8345
DOI
10.1155/2014/658589