919 Tegavivint reduces the immunosuppressive macrophage phenotype in a preclinical co-culture model...
919 Tegavivint reduces the immunosuppressive macrophage phenotype in a preclinical co-culture model of the non-small cell lung cancer tumor microenvironment
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London: BMJ Publishing Group Ltd
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English
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London: BMJ Publishing Group Ltd
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BackgroundActivation of the Wnt/ß-catenin pathway in non-small cell lung cancer (NSCLC) is associated with tumor growth and metastasis. Activation of this pathway in tumor cells may also modulate the immune tumor microenvironment (TME) by polarizing macrophages into an immunosuppressive M2-like phenotype. We tested whether treatment of co-cultures...
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919 Tegavivint reduces the immunosuppressive macrophage phenotype in a preclinical co-culture model of the non-small cell lung cancer tumor microenvironment
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TN_cdi_doaj_primary_oai_doaj_org_article_7283dcfb3415445fb1c161561fe5a718
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7283dcfb3415445fb1c161561fe5a718
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E-ISSN
2051-1426
DOI
10.1136/jitc-2021-SITC2021.919
