Exome-wide association study of levodopa-induced dyskinesia in Parkinson’s disease
Exome-wide association study of levodopa-induced dyskinesia in Parkinson’s disease
About this item
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Author / Creator
König, Eva , Nicoletti, Alessandra , Pattaro, Cristian , Annesi, Grazia , Melotti, Roberto , Gialluisi, Alessandro , Schwienbacher, Christine , Picard, Anne , Blankenburg, Hagen , Pichler, Irene , Modugno, Nicola , Ciullo, Marina , Esposito, Teresa , Domingues, Francisco S. , Hicks, Andrew A. , Zappia, Mario and Pramstaller, Peter P.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Levodopa is the standard long-term dopamine replacement therapy to treat Parkinson’s disease (PD) symptoms. With time, levodopa may induce debilitating dyskinesias (LID), the treatment of which represents a large clinically unmet need. However, time-to-LID onset varies between patients, reflecting a possible genetic component. We performed an hypot...
Alternative Titles
Full title
Exome-wide association study of levodopa-induced dyskinesia in Parkinson’s disease
Authors, Artists and Contributors
Author / Creator
Nicoletti, Alessandra
Pattaro, Cristian
Annesi, Grazia
Melotti, Roberto
Gialluisi, Alessandro
Schwienbacher, Christine
Picard, Anne
Blankenburg, Hagen
Pichler, Irene
Modugno, Nicola
Ciullo, Marina
Esposito, Teresa
Domingues, Francisco S.
Hicks, Andrew A.
Zappia, Mario
Pramstaller, Peter P.
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_729fb5b9e7544bd191b10488b78de1e8
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_729fb5b9e7544bd191b10488b78de1e8
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-99393-8