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Nuclei multiplexing with barcoded antibodies for single-nucleus genomics

Nuclei multiplexing with barcoded antibodies for single-nucleus genomics

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_72c120e589ce4b23822d48803ea3ebfb

Nuclei multiplexing with barcoded antibodies for single-nucleus genomics

About this item

Full title

Nuclei multiplexing with barcoded antibodies for single-nucleus genomics

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2019-07, Vol.10 (1), p.2907-8, Article 2907

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Single-nucleus RNA-seq (snRNA-seq) enables the interrogation of cellular states in complex tissues that are challenging to dissociate or are frozen, and opens the way to human genetics studies, clinical trials, and precise cell atlases of large organs. However, such applications are currently limited by batch effects, processing, and costs. Here, w...

Alternative Titles

Full title

Nuclei multiplexing with barcoded antibodies for single-nucleus genomics

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_72c120e589ce4b23822d48803ea3ebfb

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_72c120e589ce4b23822d48803ea3ebfb

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-10756-2

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