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Androgen Receptor Signaling Pathway in Prostate Cancer: From Genetics to Clinical Applications

Androgen Receptor Signaling Pathway in Prostate Cancer: From Genetics to Clinical Applications

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_72c710ec62324a2f9ab9a446099b76cd

Androgen Receptor Signaling Pathway in Prostate Cancer: From Genetics to Clinical Applications

About this item

Full title

Androgen Receptor Signaling Pathway in Prostate Cancer: From Genetics to Clinical Applications

Publisher

Switzerland: MDPI

Journal title

Cells (Basel, Switzerland), 2020-12, Vol.9 (12), p.2653

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI

More information

Scope and Contents

Contents

Around 80–90% of prostate cancer (PCa) cases are dependent on androgens at initial diagnosis; hence, androgen ablation therapy directed toward a reduction in serum androgens and the inhibition of androgen receptor (AR) is generally the first therapy adopted. However, the patient’s response to androgen ablation therapy is variable, and 20–30% of PCa...

Alternative Titles

Full title

Androgen Receptor Signaling Pathway in Prostate Cancer: From Genetics to Clinical Applications

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_72c710ec62324a2f9ab9a446099b76cd

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_72c710ec62324a2f9ab9a446099b76cd

Other Identifiers

ISSN

2073-4409

E-ISSN

2073-4409

DOI

10.3390/cells9122653

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