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Inhibition of platelet adhesion, thrombus formation, and fibrin formation by a potent αIIbβ3 integri...

Inhibition of platelet adhesion, thrombus formation, and fibrin formation by a potent αIIbβ3 integri...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_72cf2308bc69456798975428cdcea5c9

Inhibition of platelet adhesion, thrombus formation, and fibrin formation by a potent αIIbβ3 integrin inhibitor from ticks

About this item

Full title

Inhibition of platelet adhesion, thrombus formation, and fibrin formation by a potent αIIbβ3 integrin inhibitor from ticks

Publisher

United States: Elsevier Inc

Journal title

Research and Practice In Thrombosis And Haemostasis, 2021-01, Vol.5 (1), p.231-242

Language

English

Formats

Publication information

Publisher

United States: Elsevier Inc

More information

Scope and Contents

Contents

Ticks puncture the skin of their hosts and secrete saliva, containing antiplatelet proteins, into the blood. Here, we studied disagregin, a potent platelet‐inhibiting protein derived from the salivary glands of Ornithodoros moubata, an African soft tick. Whereas conventional αIIbβ3 antagonists contain an Arg‐Gly‐Asp (RGD) sequence for platelet inte...

Alternative Titles

Full title

Inhibition of platelet adhesion, thrombus formation, and fibrin formation by a potent αIIbβ3 integrin inhibitor from ticks

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_72cf2308bc69456798975428cdcea5c9

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_72cf2308bc69456798975428cdcea5c9

Other Identifiers

ISSN

2475-0379

E-ISSN

2475-0379

DOI

10.1002/rth2.12466

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