Eldecalcitol Inhibits LPS-Induced NLRP3 Inflammasome-Dependent Pyroptosis in Human Gingival Fibrobla...
Eldecalcitol Inhibits LPS-Induced NLRP3 Inflammasome-Dependent Pyroptosis in Human Gingival Fibroblasts by Activating the Nrf2/HO-1 Signaling Pathway
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Author / Creator
Huang, Cancan , Zhang, Chaotao , Yang, Panpan , Chao, Rui , Yue, Ziqi , Li, Congshan , Guo, Jie and Li, Minqi
Publisher
New Zealand: Dove Medical Press Limited
Journal title
Language
English
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Publisher
New Zealand: Dove Medical Press Limited
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Contents
Periodontitis is a major chronic oral disease that is accelerated by activation of the NLRP3 inflammasome and the resulting pyroptosis. According to recent studies, active vitamin D and its analogs have been reported to have great anti-inflammatory effects. However, the anti-inflammatory mechanism of a newly found vitamin D analog, eldecalcitol (ED...
Alternative Titles
Full title
Eldecalcitol Inhibits LPS-Induced NLRP3 Inflammasome-Dependent Pyroptosis in Human Gingival Fibroblasts by Activating the Nrf2/HO-1 Signaling Pathway
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_72e22def27074486bf472b439eb9365c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_72e22def27074486bf472b439eb9365c
Other Identifiers
ISSN
1177-8881
E-ISSN
1177-8881
DOI
10.2147/DDDT.S269223
