Elamipretide alleviates pyroptosis in traumatically injured spinal cord by inhibiting cPLA2-induced...
Elamipretide alleviates pyroptosis in traumatically injured spinal cord by inhibiting cPLA2-induced lysosomal membrane permeabilization
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Author / Creator
Zhang, Haojie , Chen, Yituo , Li, Feida , Wu, Chenyu , Cai, Wanta , Ye, Hantao , Su, Haohan , He, Mingjun , Yang, Liangliang , Wang, Xiangyang , Zhou, Kailiang and Ni, Wenfei
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Spinal cord injury (SCI) is a devastating injury that may result in permanent motor impairment. The active ingredients of medications are unable to reach the affected area due to the blood‒brain barrier. Elamipretide (SS-31) is a new and innovative aromatic cationic peptide. Because of its alternating aromatic and cationic groups, it freely crosses...
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Full title
Elamipretide alleviates pyroptosis in traumatically injured spinal cord by inhibiting cPLA2-induced lysosomal membrane permeabilization
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TN_cdi_doaj_primary_oai_doaj_org_article_734f6f03ea29401cb33b217fdb2f0a76
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_734f6f03ea29401cb33b217fdb2f0a76
Other Identifiers
ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-023-02690-4
