Novel cellular systems unveil mucosal melanoma initiating cells and a role for PI3K/Akt/mTOR pathway...
Novel cellular systems unveil mucosal melanoma initiating cells and a role for PI3K/Akt/mTOR pathway in mucosal melanoma fitness
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Author / Creator
Monti, Matilde , Benerini Gatta, Luisa , Bugatti, Mattia , Pezzali, Irene , Picinoli, Sara , Manfredi, Marcello , Lavazza, Antonio , Vanella, Virginia Vita , De Giorgis, Veronica , Zanatta, Lucia , Missale, Francesco , Lonardi, Silvia , Zanetti, Benedetta , Bozzoni, Giovanni , Cadei, Moris , Abate, Andrea , Vergani, Barbara , Balzarini, Piera , Battocchio, Simonetta , Facco, Carla , Turri-Zanoni, Mario , Castelnuovo, Paolo , Nicolai, Piero , Fonsatti, Ester , Leone, Biagio Eugenio , Marengo, Emilio , Sigala, Sandra , Ronca, Roberto , Perego, Michela , Lombardi, Davide and Vermi, William
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Mucosal Melanomas (MM) are highly aggressive neoplasms arising from mucosal melanocytes. Current treatments offer a limited survival benefit for patients with advanced MM; moreover, the lack of pre-clinical cellular systems has significantly limited the understanding of their immunobiology.
Five novel cell lines were obtained from patient-derive...
Alternative Titles
Full title
Novel cellular systems unveil mucosal melanoma initiating cells and a role for PI3K/Akt/mTOR pathway in mucosal melanoma fitness
Authors, Artists and Contributors
Author / Creator
Benerini Gatta, Luisa
Bugatti, Mattia
Pezzali, Irene
Picinoli, Sara
Manfredi, Marcello
Lavazza, Antonio
Vanella, Virginia Vita
De Giorgis, Veronica
Zanatta, Lucia
Missale, Francesco
Lonardi, Silvia
Zanetti, Benedetta
Bozzoni, Giovanni
Cadei, Moris
Abate, Andrea
Vergani, Barbara
Balzarini, Piera
Battocchio, Simonetta
Facco, Carla
Turri-Zanoni, Mario
Castelnuovo, Paolo
Nicolai, Piero
Fonsatti, Ester
Leone, Biagio Eugenio
Marengo, Emilio
Sigala, Sandra
Ronca, Roberto
Perego, Michela
Lombardi, Davide
Vermi, William
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_735a9e3b74ed45228ece9b45b07e75d1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_735a9e3b74ed45228ece9b45b07e75d1
Other Identifiers
ISSN
1479-5876
E-ISSN
1479-5876
DOI
10.1186/s12967-023-04784-2
