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The mrp-3 gene is involved in haem efflux and detoxification in a blood-feeding nematode

The mrp-3 gene is involved in haem efflux and detoxification in a blood-feeding nematode

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_735e251df52844b5816fe08030f3e45a

The mrp-3 gene is involved in haem efflux and detoxification in a blood-feeding nematode

About this item

Full title

The mrp-3 gene is involved in haem efflux and detoxification in a blood-feeding nematode

Publisher

England: BioMed Central Ltd

Journal title

BMC biology, 2024-09, Vol.22 (1), p.199-16, Article 199

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Haem is essential but toxic for metazoan organisms. Auxotrophic nematodes can acquire sufficient haem from the environment or their hosts in the meanwhile eliminate or detoxify excessive haem through tightly controlled machinery. In previous work, we reported a role of the unique transporter protein HRG-1 in the haem acquisition and homeostasis of...

Alternative Titles

Full title

The mrp-3 gene is involved in haem efflux and detoxification in a blood-feeding nematode

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_735e251df52844b5816fe08030f3e45a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_735e251df52844b5816fe08030f3e45a

Other Identifiers

ISSN

1741-7007

E-ISSN

1741-7007

DOI

10.1186/s12915-024-02001-0

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