A novel label-free method to determine equilibrium dissociation constants of antibodies binding to c...
A novel label-free method to determine equilibrium dissociation constants of antibodies binding to cell surface proteins
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Solution-based affinity assays are used for the selection and characterization of proteins that could be developed into therapeutic molecules. However, these assays have limitations for cell-surface proteins as in most cases their purification requires detergent solubilization and are unlikely to assume conformations in solution that resemble their...
Alternative Titles
Full title
A novel label-free method to determine equilibrium dissociation constants of antibodies binding to cell surface proteins
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_73671aa4ce83428f8cb5c158d1ce3094
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_73671aa4ce83428f8cb5c158d1ce3094
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-82288-9
