Antiretroviral drug therapy does not reduce neuroinflammation in an HIV-1 infection brain organoid m...
Antiretroviral drug therapy does not reduce neuroinflammation in an HIV-1 infection brain organoid model
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Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
HIV-1-associated neurocognitive impairment (HIV-1-NCI) is marked by ongoing and chronic neuroinflammation with loss and decline in neuronal function even when antiretroviral drug therapy (ART) successfully suppresses viral replication. Microglia, the primary reservoirs of HIV-1 in the central nervous system (CNS), play a significant role in maintai...
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Full title
Antiretroviral drug therapy does not reduce neuroinflammation in an HIV-1 infection brain organoid model
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TN_cdi_doaj_primary_oai_doaj_org_article_736a839a8b974bd3b3e8b75fc5cd0d0b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_736a839a8b974bd3b3e8b75fc5cd0d0b
Other Identifiers
ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-025-03375-w
