Log in to save to my catalogue

High-Level Production of scFv-Fc Antibody Using an Artificial Promoter System with Transcriptional P...

High-Level Production of scFv-Fc Antibody Using an Artificial Promoter System with Transcriptional P...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7398657d0407463190dfe4ca4b3c4f7a

High-Level Production of scFv-Fc Antibody Using an Artificial Promoter System with Transcriptional Positive Feedback Loop of Transactivator in CHO Cells

About this item

Full title

High-Level Production of scFv-Fc Antibody Using an Artificial Promoter System with Transcriptional Positive Feedback Loop of Transactivator in CHO Cells

Publisher

Switzerland: MDPI AG

Journal title

Cells (Basel, Switzerland), 2023-11, Vol.12 (22), p.2638

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

With the increasing demand for therapeutic antibodies, CHO cells have become the de facto standard as producer host cells for biopharmaceutical production. High production yields are required for antibody production, and developing a high-titer production system is increasingly crucial. This study was established to develop a high-production system...

Alternative Titles

Full title

High-Level Production of scFv-Fc Antibody Using an Artificial Promoter System with Transcriptional Positive Feedback Loop of Transactivator in CHO Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_7398657d0407463190dfe4ca4b3c4f7a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7398657d0407463190dfe4ca4b3c4f7a

Other Identifiers

ISSN

2073-4409

E-ISSN

2073-4409

DOI

10.3390/cells12222638

How to access this item