High-Level Production of scFv-Fc Antibody Using an Artificial Promoter System with Transcriptional P...
High-Level Production of scFv-Fc Antibody Using an Artificial Promoter System with Transcriptional Positive Feedback Loop of Transactivator in CHO Cells
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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With the increasing demand for therapeutic antibodies, CHO cells have become the de facto standard as producer host cells for biopharmaceutical production. High production yields are required for antibody production, and developing a high-titer production system is increasingly crucial. This study was established to develop a high-production system...
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High-Level Production of scFv-Fc Antibody Using an Artificial Promoter System with Transcriptional Positive Feedback Loop of Transactivator in CHO Cells
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TN_cdi_doaj_primary_oai_doaj_org_article_7398657d0407463190dfe4ca4b3c4f7a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_7398657d0407463190dfe4ca4b3c4f7a
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ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells12222638