Upregulated METTL3 promotes metastasis of colorectal Cancer via miR-1246/SPRED2/MAPK signaling pathw...
Upregulated METTL3 promotes metastasis of colorectal Cancer via miR-1246/SPRED2/MAPK signaling pathway
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Author / Creator
Peng, Wen , Li, Jie , Chen, Ranran , Gu, Qiou , Yang, Peng , Qian, Wenwei , Ji, Dongjian , Wang, Qingyuan , Zhang, Zhiyuan , Tang, Junwei and Sun, Yueming
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Contents
m6A modification has been proved to play an important role in many biological processes. METTL3 as the main methyltransferase for methylation process has been found to be upregulated in many cancers, including CRC. Here, we investigate m6A modification and the underlying mechanism of METTL3 in the development of CRC.
The expression of METTL3 was...
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Full title
Upregulated METTL3 promotes metastasis of colorectal Cancer via miR-1246/SPRED2/MAPK signaling pathway
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TN_cdi_doaj_primary_oai_doaj_org_article_739eab4131b4484fb437a9965acb14d3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_739eab4131b4484fb437a9965acb14d3
Other Identifiers
ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-019-1408-4
