FAT1 expression in T-cell acute lymphoblastic leukemia (T-ALL) modulates proliferation and WNT signa...
FAT1 expression in T-cell acute lymphoblastic leukemia (T-ALL) modulates proliferation and WNT signaling
About this item
Full title
Author / Creator
Liebig, Sven , Neumann, Martin , Silva, Patricia , Ortiz-Tanchez, Jutta , Schulze, Veronika , Isaakidis, Konstandina , Schlee, Cornelia , Schroeder, Michael P. , Beder, Thomas , Morris, Luc G. T. , Chan, Timothy A. , Bastian, Lorenz , Burmeister, Thomas , Schwartz, Stefan , Gökbuget, Nicola , Mochmann, Liliana H. and Baldus, Claudia D.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
FAT atypical cadherin 1 (FAT1), a transmembrane protein, is frequently mutated in various cancer types and has been described as context-dependent tumor suppressor or oncogene. The
FAT1
gene is mutated in 12–16% of T-cell acute leukemia (T-ALL) and aberrantly expressed in about 54% of T-ALL cases contrasted with absent expression in normal T-...
Alternative Titles
Full title
FAT1 expression in T-cell acute lymphoblastic leukemia (T-ALL) modulates proliferation and WNT signaling
Authors, Artists and Contributors
Author / Creator
Neumann, Martin
Silva, Patricia
Ortiz-Tanchez, Jutta
Schulze, Veronika
Isaakidis, Konstandina
Schlee, Cornelia
Schroeder, Michael P.
Beder, Thomas
Morris, Luc G. T.
Chan, Timothy A.
Bastian, Lorenz
Burmeister, Thomas
Schwartz, Stefan
Gökbuget, Nicola
Mochmann, Liliana H.
Baldus, Claudia D.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_73aaef34737c42fdadc2a0d1ed2b4094
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_73aaef34737c42fdadc2a0d1ed2b4094
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-27792-0
