Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2R47H
Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2R47H
About this item
Full title
Author / Creator
Kotredes, Kevin P , Oblak, Adrian , Pandey, Ravi S , Lin, Peter Bor-Chian , Garceau, Dylan , Williams, Harriet , Uyar, Asli , O'Rourke, Rita , O'Rourke, Sarah , Ingraham, Cynthia , Bednarycek, Daria , Belanger, Melisa , Cope, Zackary , Foley, Kate E , Logsdon, Benjamin A , Mangravite, Lara M , Sukoff Rizzo, Stacey J , Territo, Paul R , Carter, Gregory W , Sasner, Michael , Lamb, Bruce T and Howell, Gareth R
Publisher
Switzerland: Frontiers Research Foundation
Journal title
Language
English
Formats
Publication information
Publisher
Switzerland: Frontiers Research Foundation
Subjects
More information
Scope and Contents
Contents
Late-onset Alzheimer's disease (AD; LOAD) is the most common human neurodegenerative disease, however, the availability and efficacy of disease-modifying interventions is severely lacking. Despite exceptional efforts to understand disease progression
legacy amyloidogenic transgene mouse models, focus on disease translation with innovative mouse...
Alternative Titles
Full title
Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2R47H
Authors, Artists and Contributors
Author / Creator
Oblak, Adrian
Pandey, Ravi S
Lin, Peter Bor-Chian
Garceau, Dylan
Williams, Harriet
Uyar, Asli
O'Rourke, Rita
O'Rourke, Sarah
Ingraham, Cynthia
Bednarycek, Daria
Belanger, Melisa
Cope, Zackary
Foley, Kate E
Logsdon, Benjamin A
Mangravite, Lara M
Sukoff Rizzo, Stacey J
Territo, Paul R
Carter, Gregory W
Sasner, Michael
Lamb, Bruce T
Howell, Gareth R
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_73c95daef488457a898befbeee08ddc2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_73c95daef488457a898befbeee08ddc2
Other Identifiers
ISSN
1663-4365
E-ISSN
1663-4365
DOI
10.3389/fnagi.2021.735524
