Noninvasive detection of pancreatic ductal adenocarcinoma using the methylation signature of circula...
Noninvasive detection of pancreatic ductal adenocarcinoma using the methylation signature of circulating tumour DNA
About this item
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Author / Creator
Wu, Huanwen , Guo, Shiwei , Liu, Xiaoding , Li, Yatong , Su, Zhixi , He, Qiye , Liu, Xiaoqian , Zhang, Zhiwen , Yu, Lianyuan , Shi, Xiaohan , Gao, Suizhi , Wang, Huan , Pan, Yaqi , Ma, Chengcheng , Liu, Rui , Dai, Menghua , Jin, Gang and Liang, Zhiyong
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Pancreatic ductal adenocarcinoma (PDAC) has the lowest overall survival rate primarily due to the late onset of symptoms and rapid progression. Reliable and accurate tests for early detection are lacking. We aimed to develop a noninvasive test for early PDAC detection by capturing the circulating tumour DNA (ctDNA) methylation signature in blood.
Alternative Titles
Full title
Noninvasive detection of pancreatic ductal adenocarcinoma using the methylation signature of circulating tumour DNA
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_73d080e2f61b4541b21002f7252ee34c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_73d080e2f61b4541b21002f7252ee34c
Other Identifiers
ISSN
1741-7015
E-ISSN
1741-7015
DOI
10.1186/s12916-022-02647-z
