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SLC10A4 regulates IgE-mediated mast cell degranulation in vitro and mast cell-mediated reactions in...

SLC10A4 regulates IgE-mediated mast cell degranulation in vitro and mast cell-mediated reactions in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_741c7a5b20964df38f985281738b71f6

SLC10A4 regulates IgE-mediated mast cell degranulation in vitro and mast cell-mediated reactions in vivo

About this item

Full title

SLC10A4 regulates IgE-mediated mast cell degranulation in vitro and mast cell-mediated reactions in vivo

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-04, Vol.7 (1), p.1085-12, Article 1085

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Mast cells act as sensors in innate immunity and as effector cells in adaptive immune reactions. Here we demonstrate that SLC10A4, also referred to as the vesicular aminergic-associated transporter, VAAT, modifies mast cell degranulation. Strikingly,
Slc10a4
−/−
bone marrow-derived mast cells (BMMCs) had a significant reduction in the rele...

Alternative Titles

Full title

SLC10A4 regulates IgE-mediated mast cell degranulation in vitro and mast cell-mediated reactions in vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_741c7a5b20964df38f985281738b71f6

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_741c7a5b20964df38f985281738b71f6

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-017-01121-8

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