Aggresome formation promotes ASK1/JNK signaling activation and stemness maintenance in ovarian cance...
Aggresome formation promotes ASK1/JNK signaling activation and stemness maintenance in ovarian cancer
About this item
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Author / Creator
Chen, Yurou , Qiang, Yulong , Fan, Jiachen , Zheng, Qian , Yan, Leilei , Fan, Guanlan , Song, Xiaofei , Zhang, Nan , Lv, Qiongying , Xiong, Jiaqiang , Wang, Jingtao , Cao, Jing , Liu, Yanyan , Xiong, Jie , Zhang, Wei and Li, Feng
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Aggresomes are the product of misfolded protein aggregation, and the presence of aggresomes has been correlated with poor prognosis in cancer patients. However, the exact role of aggresomes in tumorigenesis and cancer progression remains largely unknown. Herein, the multiomics screening reveal that OTUD1 protein plays an important role in retaining...
Alternative Titles
Full title
Aggresome formation promotes ASK1/JNK signaling activation and stemness maintenance in ovarian cancer
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_74237dd664bc419ca7fc648dec614ded
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_74237dd664bc419ca7fc648dec614ded
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-45698-x
